Deeksha Seth was born on February 14, 1987 in Delhi, India. She competed at the Femina Miss India pageant where she placed in the Top 10 and won the Fresh Face Award.
In 2010, she made her acting debut playing the role of Pooja in the 2010 Telugu film Vedam. The following year, she appeared in the movies Mirapakaay and Wanted. Also in 2011, she made her debut in the Tamil cinema with Rajapattai.
She then resumed to starring mainly in Telugu features with the 2012 motion pictures Nippu, Uu Kodathara? Ulikki Padathara? and Rebel. She stars in the upcoming Tamil action thriller movie Vettai Mannan.